Calcium oxalate nephrolithiasis: Defective oxalate transport
نویسندگان
چکیده
منابع مشابه
Cystic fibrosis and calcium oxalate nephrolithiasis.
During the past six years, we have treated eight patients with cystic fibrosis (CF) for nephrolithiasis. In seven patients, the stones were comprised of calcium oxalate. Another six patients had calcium oxalate crystalluria. In our CF population of 140 patients, this represents a cumulative incidence of calcium oxalate nephrolithiasis of 5.7 percent and an additional 4.2 percent incidence of cr...
متن کاملEffect of citrate on the urinary excretion of calcium and oxalate: relevance to calcium oxalate nephrolithiasis.
Studies in 24 recurrent oxalate stone-formers have shown that values for urinary calcium excretion for this group on at-home diets vary significantly (P less than 0.001) more than values for creatinine excretions. By placing stone-formers on controlled in-hospital diets and measuring their calcium excretions, we were able to predict probable outpatient hypercalciuria (greater than 7.5 mmol/day)...
متن کاملNormal calcium oxalate crystal growth inhibition in severe calcium oxalate nephrolithiasis.
Urine from mammalian kidneys is regularly supersaturated with respect to calcium oxalate monohydrate, the most common solid phase in human nephrolithiasis, and also inhibits the nucleation, growth, and aggregation of calcium oxalate crystals. Nephrolithiasis is often associated with increased supersaturation, and it is assumed that this increase overbalances the inhibition effects, causing ston...
متن کاملSulfate and thiosulfate inhibit oxalate transport via a dPrestin (Slc26a6)-dependent mechanism in an insect model of calcium oxalate nephrolithiasis.
Nephrolithiasis is one of the most common urinary tract disorders, with the majority of kidney stones composed of calcium oxalate (CaOx). Given its prevalence (US occurrence 10%), it is still poorly understood, lacking progress in identifying new therapies because of its complex etiology. Drosophila melanogaster (fruitfly) is a recently developed model of CaOx nephrolithiasis. Effects of sulfat...
متن کامل'Bad dietary habits' and recurrent calcium oxalate nephrolithiasis.
[UUrea×V (mmol/day)×0.18]+13 A 32-year-old truck driver had previously been treated =Protein consumption (g/day) with allopurinol because of hyperuricaemia and gouty arthritis. After having first formed a kidney stone at (adapted from [5]); age 20, he had passed calculi annually for 8 years before he finally underwent ESWL for bilateral radioit amounted to 108.1 g or 1.25 g/kg BW per day. The o...
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ژورنال
عنوان ژورنال: Kidney International
سال: 1991
ISSN: 0085-2538
DOI: 10.1038/ki.1991.162